Select Published Research — Acacia Clinics

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Research contributed by an Acacia Researcher as a first or co-author.

THERAPEUTIC RESEARCH TOPICS

Alzheimer's Disease

Anxiety

Cognitive Processes & Therapeutic Approaches

Depression

Obsessive-Compulsive Disorder (OCD)

Pain and Migrain

Post-traumatic Stress Disorder (PTSD)

Schizophrenia/Maniac Disorder

Alzheimer's Disease

OViTAD: Optimized vision transformer to predict various stages of Alzheimer’s disease using resting-state fMRI and structural MRI data

2023

Sarraf, S., Sarraf, A., DeSouza, D. D., Anderson, J. A. E., Kabia, M.

MCADNNet: Recognizing stages of cognitive impairment through efficient convolutional fMRI and MRI neural network topology models

2019

S. Sarraf, D. D. Desouza, J. A. E. Anderson, & C. Saverino

DeepAD: Alzheimer’s disease classification via deep convolutional neural networks using MRI and fMRI

2017

Sarraf, S., DeSouza D. D., Anderson, J.A. , Tofighi G.

Anxiety

Acoustic and linguistic features of impromptu speech and their association with anxiety: validation study

2022

Teferra, B. G., Borwein, S., DeSouza, D. D., Simpson, W., Rheault, L., & Rose, J.

Screening for Generalized Anxiety Disorder From Acoustic and Linguistic Features of Impromptu Speech: Prediction Model Evaluation Study

2022

Teferra, B. G., Borwein, S., DeSouza, D. D., & Rose, J.

Psychometric Approach to Speech Feature Analysis as an Objective Measure of Anxiety

2021

DeSouza, D., Xu, M., Fidalgo, C., Robin, J., & Simpson, W.

Cognitive Processes & Therapeutic Approaches

The Stanford Hypnosis Integrated with Functional Connectivity-targeted Transcranial Stimulation (SHIFT): A Preregistered Randomized Controlled Trial

2023

Afik, F., Bishop, J.H., Stimpson, K.H., Phillips, A., Gulser, M., Amin, H., Nejad, R., DeSouza, D.D., Geoly, A.D., Kallioniemi, E., Jo, B., Williams, N.R., Spiegel, D.

Association between anterior cingulate neurochemical concentration and individual differences in hypnotizability

2020

DeSouza, D. D., Stimpson, K. H., Baltusis, L., Sacchet, M. D., Gu, M., Hurd, R., Wu, H., Yeomans, D. C., Willliams, N., & Spiegel, D.

Identification of common neural circuit disruptions in emotional processing across psychiatric disorders

2019

McTeague, L. M., Rosenberg, B. M., Lopez, J. W., Carreon, D. M., Huemer, J., Jiang, Y., Chick, C. F., Eickhoff, S. B., & Etkin, A.

Mentalization-based treatment for adolescents: the framework for work with suicide and self-injurious behaviors

2020

Rossouw, T., Muir, O., & Williams, L. L.

Identification of common neural circuit disruptions in cognitive control across psychiatric disorders

2017

McTeague, L. M., Huemer, J., Carreon, D. M., Jiang, Y., Eickhoff, S. B., & Etkin, A.

Depression

Accelerated intermittent theta burst transcranial magnetic stimulation is a safe and efficacious treatment for adolescents with depressive symptoms

2023

Nakano, E., Veerapal, C., DeSouza, D., Meng, N., & Carreon, D.

Accelerated intermittent-theta burst stimulation for the treatment of adolescent depression: a case series 2023

2023

Nakano, E., Sedaros, P., Hoang, V., Pi, J., Marco, J., Shankar, S., Pai, G., Luna, A., Siddiqi, S., Meng, N., DeSouza, D., & Carreon, D.

Accelerated theta-burst stimulation using individualized fMRI-based targets in adolescents with depression

2023

Nakano, E., Sedaros, P., Hoang, V., Pi, J., Marco, J., Shankar, S., Pai, G., Luna, A., Siddiqi, S., Meng, N., DeSouza, D., & Carreon, D.

Deep TMS H1 Coil treatment for depression: results from a large post marketing data analysis

2023

Tendler, A., Goerigk, S., Zibman, S., Ouaknine, S., Harmelech, T., Pell, G. S., Zangen, A., Harvey, S. A., Grammer, G., Stehberg, J., Adefolarin, O., Muir, O., MacMillan, C., Ghelber, D., Duffy, W., Mania, I., Faruqui, Z., Munasifi, F., Antin, T., … Roth, Y.

Evaluating the utility of daily speech assessments for monitoring depression symptoms

2023

Gumus, M., DeSouza, D. D., Xu, M., Fidalgo, C., Simpson, W., & Robin, J.

Stanford Neuromodulation Therapy (SNT): a Double-Blind Randomized Controlled Trial

2022

Cole, E. J., Phillips, A. L., Bentzley, B. S., Stimpson, K. H., Nejad, R., Barmak, F., Veerapal, C., Khan, N., Cherian, K., Felber, E., Brown, R., Choi, E., King, S., Pankow, H., Bishop, J. H., Azeez, A., Coetzee, J., Rapier, R., Odenwald, N., Carreon, D., … Williams, N. R.

Deep TMS for major depression, interim post-marketing analysis of 1040 patients

2020

Harvey, S. A., Tendler, A., DeLuca, M., Stehberg, J., Naimark, R., Schmidt, D., Muir, O., McMillan, C., Shakir, S., Antin, T., Ghelber, D., Duffy, W., Lender, N., Goodman, M., Isserles, M., Melman, K., Cabrera, J., Jr., Munasifi, F. A., Jones, D., … Roth, Y.

High-dose spaced theta-burst TMS as a rapid-acting antidepressant in highly refractory depression

2018

Williams, N. R., Sudheimer, K. D., Bentzley, B. S., Pannu, J., Stimpson, K. H., Duvio, D., Cherian, K., Hawkins, J., Scherrer, K. H., Vyssoki, B., DeSouza, D., Raj, K. S., Keller, J., & Schatzberg, A. F

Cortical Thickness Changes Following Accelerated Neuromodulation Therapy for Treatment-Resistant Depression Predict Depression Scores at One-Month

2021

DeSouza, D., Bentzley, B., Cole, E., Phillips, A., Nejad, R., Stimpson, K., Schatzberg, A., Sudheimer, K., & Williams, N.

Global connectivity and local excitability changes underlie antidepressant effects of repetitive transcranial magnetic stimulation

2020

Eshel, N., Keller, C. J., Wu, W., Jiang, J., Mills-Finnerty, C., Huemer, J., Wright, R., Fonzo, G. A., Ichikawa, N., Carreon, D., Wong, M., Yee, A., Shpigel, E., Guo, Y., McTeague, L., Maron-Katz, A., & Etkin, A.

Rapid remission of depression using sequential bilateral theta burst dTMS

2019

Muir, O., MacMillan, C., Khan, M., Sang, L., & Aron, T.

Natural Language Processing as an Emerging Tool to Detect Late-Life Depression

2021

DeSouza, D. D., Robin, J., Gumus, M., & Yeung, A.

Obsessive-Compulsive Disorder (OCD)

Long-term outcomes of a course of deep TMS for treatment-resistant OCD

2022

Harmelech, T., Tendler, A., Arikan, M. K., Çetin, H. L., Esmeray, M. T., Ilhan, R., Vidrine, R., Muir, O., MacMillan, C., Sinclair, R., Shakir, S., Kent, D., Evangelidis, N., & Roth, Y.

Real-world efficacy of deep TMS for obsessive-compulsive disorder: post-marketing data collected from twenty-two clinical sites

2021

Roth, Y., Tendler, A., Arikan, M. K., Vidrine, R., Kent, D., Muir, O., MacMillan, C., Casuto, L., Grammer, G., Sauve, W., Tolin, K., Harvey, S., Borst, M., Rifkin, R., Sheth, M., Cornejo, B., Rodriguez, R., Shakir, S., Porter, T., … Zangen, A.